Tough reading on a Sat morning, but felt needed to try hard. Good that international groups are trying to follow potential biological threats, which has been going on for decades. Evidently pinning down actual pathways is complex, because nature is complex. But these explanations are interesting to follow. And recommendations seem solid, if everyone can follow them.
Serial passage in the lab , using mice, still sounds like a plausible explanation, not obviated by this mulitstep, LLM analysis. No DNA supplies ordered from biolabs, no genetic signature, no fiddling with the biochemistry otherwise, just keeping a few thousand mice in the lab and doing serial passage.
Why is this not a significant possibility?
It came out of Borswana, a Chinese satrapy for all practical purposes.
The idea the virus used a single immunocompromised person to evolve all those mutations in short order really seems far-fetched. And how did that happen? What would have facilitated its rapid promulgation through worldwide populace?
Pardon an idiological question but just why would anyone go to this trouble to create this virus? That question alone would bias me to disbelieve lab creation.
If you disbelieve the notion because it's too much trouble, then I'd ask the question- why would anyone make GOF organisms in the first place? It is certainly not to study for new vaccines .It's alot of 'trouble'. It seems logical to me that anyone who was fiddling with the genetics of a virus to begin with, and concocted a unit that was infectious but not very lethal as was the first agent, might consider making it more infectious.
GOF performed to create viruses of enhanced lethality, infection, or both...either to develop treatment strategies for such viruses or to create bioweapons. This virus does not appear likely to fit,either scenario. And there is onheck of amount if work involved in creating these critters
Have wondered why Baysian not used more. It eliminates the bias introduced by normal statistics assuming all parameters being measured are known
thank you for that comment, Dr. Nash
My comment on the Omicron post accidentally became attached to the Bird Flu post. So sorry!
Has an AI analysis been done on the original covid-19 virus to get its determination on the likelihood of the original virus origins?
It was my initial analysis demo project. The tool is more sophisticated now and I intend to re-run at some point. https://www.malone.news/p/the-invisible-inspectors-how-artificial
Has this technology been trained to pick up on Ralph Baric’s “noseeum” method of gene insertion?
I believe that the specialty sequence analysis software packages have. I have not integrated those in yet. This is a demo project at this point.
Thank you!
Tough reading on a Sat morning, but felt needed to try hard. Good that international groups are trying to follow potential biological threats, which has been going on for decades. Evidently pinning down actual pathways is complex, because nature is complex. But these explanations are interesting to follow. And recommendations seem solid, if everyone can follow them.
Serial passage in the lab , using mice, still sounds like a plausible explanation, not obviated by this mulitstep, LLM analysis. No DNA supplies ordered from biolabs, no genetic signature, no fiddling with the biochemistry otherwise, just keeping a few thousand mice in the lab and doing serial passage.
Why is this not a significant possibility?
It came out of Borswana, a Chinese satrapy for all practical purposes.
The idea the virus used a single immunocompromised person to evolve all those mutations in short order really seems far-fetched. And how did that happen? What would have facilitated its rapid promulgation through worldwide populace?
-M R Weiss, MD
Pardon an idiological question but just why would anyone go to this trouble to create this virus? That question alone would bias me to disbelieve lab creation.
If you disbelieve the notion because it's too much trouble, then I'd ask the question- why would anyone make GOF organisms in the first place? It is certainly not to study for new vaccines .It's alot of 'trouble'. It seems logical to me that anyone who was fiddling with the genetics of a virus to begin with, and concocted a unit that was infectious but not very lethal as was the first agent, might consider making it more infectious.
GOF performed to create viruses of enhanced lethality, infection, or both...either to develop treatment strategies for such viruses or to create bioweapons. This virus does not appear likely to fit,either scenario. And there is onheck of amount if work involved in creating these critters