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Henry Lahore's avatar

Beberine is one of 17 supplements that increase the amount of vitamin D that actually gets to the cells by increasing the activation of the Vitamin D Receptor. Here is one of the 20 Berberine pages on VitaminDwiki. https://vitamindwiki.com/pages/berberine-an-antioxidant-that-activates-the-vitamin-d-receptor-many-studies/. There are links to all 20 at the bottom of the page

Thomas A Braun RPh's avatar

Unfortunately the Medical profession doesn't want to admit the true value of maintaining the value of D at or above 50 ng's for good health. Reduces the risk of many many disease states. I boosted my wife's D from 9 ng to a much higher value and her AG1 went from 9 to 5.2. I keep writing about the value of D and nothing changes. Only proprietary, profitable and patented products prevail.

Lucia P's avatar

My 71yo husband was scheduled for his 6mo checkup last week. Blood work did not include vit D levels. You can't treat something you do not want to find.

beccar1954's avatar

You have to request a vitamin D test. Depending if you have a condition related to vitamin D deficiency, such as osteoporosis, your insurance might pay for it. However, it’s not that expensive, and you can get home vitamin D tests.

Thomas A Braun RPh's avatar

Intentional to reduce the frequency of testing to maintain the current medical paradigm

Tory77simplifyfocus's avatar

Thank you. This completely supports the reason my general dr’s… exhort to cut Vitamin D.

Sadly, my first influence was during Covid 19 and Dr. Zev Zelenco was one large light in a dark time. Thank you for more information on Berberine as well.

PutativePathogen's avatar

Years ago, I remember being convinced that drug prices were justified because of the billions spent on R&D.

My naive assumption was that these drugs were developed to be curative, or at least palliative. Knowing that they exist only to enrich their developers, makers, marketers, dispensers, medical journals and portfolio managers is a sickening betrayal. But I'm glad that I know, and can now take responsibility for my own choices, soberly made. As always, thanks for the information. It matters.

Thomas A Braun RPh's avatar

Marketing costs to drugs supersede research costs!

Tracy Kolenchuk's avatar

Read the package labels on your drugs. Look for the word CURE. You won't find it.

Paula Kroll's avatar

I have now been using berberine for a few months, after I heard a YouTube physician recommend it for gut health. As a life long IBS sufferer, I was at my wit's end. Nothing worked as far as dietary changes. FODMAPS was nearly impossible to stick to plus it contradicted my commitment to healthy eating.

Although my situation is anecdotal rather than clinical, I have been symptom free for months. I have been off imodium, peppermint capsules and Pepto since I began the berberine. The other benefits you mention will hopefully show in my next metabolic panel.

Thank you Drs. Malone!!

KC & the Sunshine's avatar

What brand of berberine are you using, pls? I have Double Wood Supplements brand and so far, I feel like it’s slightly curbing my appetite and it def curbs my appetite for sweets/late night snacks. I am considering using 2-3 brands so as to cover any weak spots of one brand over the other.

Paula Kroll's avatar

I use Thorne 1000 mg once a day, with a meal. Usually at dinnertime. I haven't felt a need to try other brands. I wish you good health.

I think it definitely curbs my sweet cravings in the evening.

dennis's avatar

I just recently started taking dihydroberberine. Supposedly more potent.

Thomas A Braun RPh's avatar

Check out probiotics and prebiotics!

Also, read the labels avoid toxic ingredients like Sucralose and aspartame and carrageenan!

Paula Kroll's avatar

Also high fructose corn syrup, maltodextrin. I read labels for everything.

No seed oils, period.

Tory77simplifyfocus's avatar

Preferring dietary probiotics to a pill, I am curious on your recommendation for best way to get pro and pre biotics.

This is such a target for false marketing.

Thomas A Braun RPh's avatar

Rx drugs for GI issues reek of similar false marketing. Costco carries some good probiotics. Band aid pills don’t solve root causes.

Jane Maples's avatar

What berberine do you take?buy?

Paula Kroll's avatar

Thorne, by mail order from Thorne.com.

Physician recommended.

JanC1955's avatar

You can also get it from several online sellers, including Amazon. Cost for 60 capsules is $44.

beccar1954's avatar

Watch out for supplements on Amazon. There has been a lot of fraud, with labels being applied over labels of completely different products.

Professor Mus's avatar

As a trained pharmacist and an herbalist, I think this mindset of comparing plant medicine to pharmaceutical products is misleading and dangerous. Misleading because plants, unlike pharmaceutical products, contain many alkaloids, terpenes, phenols, and other compounds that may (or may not) work synergistically in the body to improve health. The compounds themselves may work together, or they may work independently to affect different organs and/or physiologic systems. For example, one reason berberine helps the gut biome is because of its bitter properties, which stimulates digestive enzymes and acids to improve the gut's terrain. That said, most supplements isolate the berberine from the other beneficial constituents found in berberine-containing plants such as barberry, Oregon grape, yellow root, and goldenseal (please do not source from goldenseal as it is an endangered plant).

Dangerous because most people equate pharmaceuticals to plants and, therefore, expect the same effects and outcomes--immediately. Most plant medicines work slowly, effecting organic changes rather than abrupt effects. When immediate relief isn't obtained, may will abandon plant medicines and go for the pills, tablets, and injections which promise miraculous change--now. It is this mindset which I hope to change in my own growing practice, and which really does get to the foundational heart of holistic health.

As for berberine... I use berberine in my practice, utilizing it in bitters preparations and in teas. I forage the berries and, in the fall, the roots of common and Japanese barberry that grow on my land. The berries have small amounts of berberine, so these I dry and throw into my daily infusions. The roots I dry, tincture, and incorporate into one of my bitters preparations. From my own (and several of my clients') 'anecdotal' experiences, I find both tea and bitters lowers my carbohydrate cravings and assists with weight reduction. The sugar craving abatement is immediate, and helpful to prevent overeating, especially at night. The weight loss is gradual, which is the best way to permanently shed pounds.

Thanks for the update on berberine. I hope readers come to appreciate the slow and natural benefits of plant medicines. Peace...

KC & the Sunshine's avatar

This is intriguing.

Do you by chance sell any of your tinctures?

beccar1954's avatar

The other constituents in whole herbs improves absorption of berberine, just like the other components of turmeric aids the absorption of curcumin. Each of the berberine-containing herbs has unique properties with uses different from pure berberine. Traditional Chinese Medicine does use berberine sulfate in some herbal formulas, and for the general public with no knowledge of herbal medicine, berberine can be very helpful. However, it’s often best to use whole herbs if done with proper information about the particular herb.

Thomas A Braun RPh's avatar

What are your views on how synthetic Rx drugs deplete key nutritients required for cellular health?

Thomas A Braun RPh's avatar

The Chinese have spent 5 centuries refining their understanding of which botanical have a positive impact on health and disease states. Until Rockefeller created the allopathic medicine model, botanicals were the mainstay of pharmacies around the world. In 1997, I visited a Shanghai hospital and the pharmacy was still dominated with botanicals. Synthetic drugs are less costly to produce and are vastly more profitable. You are being too kind to GLP1 since two thirds of the weight loss are from degradation of muscle mass and only one third from adipose tissue. Check out the lawsuits that are multiplying claiming GLP1 has caused great harm and death. It appears it is a slow developing harmful drug. My Gail lost her eye co-ordination after only three months use. Muscle degradation of eye muscles. Diagnosed with inflammation of retinal cells.

KC & the Sunshine's avatar

Follow up to the exponential autoimmune issues everywhere:

Vaccines tell the body to mount a defense to ____ whatever illness, right?

HOW does the body know to

mount a defense against chicken pox yet NOT mount a defense against canine fur, if canine cells are in the shot? Are we CREATING pet dander allergies via vaccines?

How does the body know to mount a defense against mumps— or whatever— but NOT mount a defense against the body—- as in autoimmune issues like diabetes, if there are fragments of fetal cells— fragments of little bodies, in every vial of vaccines?

Think about it.

What made me think abt it was

an old comedy routine done by George Carlin— I think. It’s something like, he accidentally took midol thinking it was aspirin and now he is deeply concerned that the midol is still languishing around in his body, pointlessly searching for an ovary to help! 😂😂😂

In a way, are we not doing this to babies? “Here, mount a defense to all this toxic crap! Mumps, polio, alcohol, formaldehyde, animal cells, fetal cells, peanuts, etc.” 🥜

And in the process we kill the perfectly designed gut biome and injury the fabulously designed brain, inflaming it on Day 1.

We are NOT born pharmaceutically deficient.

We are fearfully and wonderfully made.

Love Activist's avatar

I've been taking berberine for years and I notice consistent and gentle support.

Jonny's avatar

I've given into the GLP-1 agonist. It's my opinion that decades of learned poor habits and a culture that is awash in ultra-processed foods and refined carbs generally have left me nearly unable to listen to my own body's cues. I'm trying to me mindful and make better choices. Poor habits and food preferences learned in childhood have been devilishly hard to break. My goal is to taper the dose until I am better able to maintain a weight. Doc says I may never get to go to zero...

beccar1954's avatar

Give it time and keep working on improving your diet. Eventually the foods that used to be irresistible will taste disgusting. Read everything you can about health and diet. I recommend the website and books by Cate Shanahan MD. The processed food you need to avoid above all else is seed oils, because they damage your metabolism, your cell membranes, and mitochondria, so that you can’t burn your body fat for energy. As a result, you need frequent sugar snacks to maintain your energy for short periods, leading to energy crashes and more sugar. Don’t believe that you are a hopeless victim of the ultra-processed food culture. You can break free from it over time.

Jonny's avatar

Thank you for the reply. I might be a little more aware and proactive about dietary issues than my brief post let on. But the point remains that our culture is awash in garbage foods, which can make eating healthily in a social context difficult.

beccar1954's avatar

That’s true. Sometimes you can bring your own food, and other times make the best choices that you can. If you are a sugarholic avoid that, because it’s easy to get re-addicted. Whatever your binge foods are make a point of avoiding. From a nutritional view it’s better to eat pizza than cake. After a period of good eating, you won’t feel well after eating junk food, and it’s an incentive not too, even in a social situation.

Deb Ann's avatar

I’ve been taking it for over nine months as a “helpful” supplement to keep my stage 4 cancer (for 3. years) at bay. I have had no gastrointestinal side effects and I have a very sensitive stomach. I’m taking quite a few repurposed drugs/supplements to avoid the toxic chemo, etc. Good health to all. Robert encouraging a healthy diet and exercise is a must for everyone.

Dr. Robert W. Malone's avatar

We have never had any gastrointestinal side effects from taking it either.

KC & the Sunshine's avatar

It’s sickening that so many of these issues begin at birth— via Big pHARM-us and the medical establishment.

C-sections start the whole gut-screw-up thing because something magical that happens via a normal birth cannot occur with a C-Section. (*Not trying to make moms feel bad at all! Sometimes a C-Section has to happen. Sometimes it’s a convenience thing for the OB. I get it.)

Then, on Day 1, they inject baby with HepB, although they previously tested Mom for it, and she likely tested negative. “Just in case…” is the big reasoning here. Ask Alexa or ChatGPT how many deaths there are from HepB per year. US population is around 349 million. Consider the odds of your baby being promiscuous or sharing dirty needles or being in contact with someone who does and the likelihood that Baby will need this “preventative measure”— that in fact prevents nothing.

THEN they pile on the heinous “vitamin K” shot, which makes the blood tar like and no longer able to get into nooks and crannies to heal any trauma Baby may have suffered during birth. It makes them super sleepy, which leads to poor latching and feeding, which can lead to formula feeding which ends in gut microbiome being screwed up. The shot itself starts to

mess things up, then the “cure” finishes the job.

So, welcome to the world, Baby! You MUST be pharmaceutically deficient!

Then we go on to further vaccinate them at 2 months, 4 months, 6 months and so on.

Go on the CDC website or JusttheInserts.com and find the vaccine ingredients in about Section 5.0 or 6.0.

Ask yourself what

alcohol

formaldehyde

polysorbates

HEK (Human Embryo Kidney) cells

MRC-38 (aborted baby fetal cells, 38th iteration!)

WI-8 (another aborted baby fetus, different sex!) **Has anyone considered that the extreme skyrocketing autoimmune issues may be related to VACCINES, wherein there are fragmented cells from the BODIES of BOTH SEXES of babies? Autoimmune being, the attack of one’s own BODY?

canine/equine/porcine (porky pig) cells (animal dander allergies that no one in your family tree had, anyone?)

peanut/egg proteins (rampant peanut allergies, anyone?)

aluminum

etc. is doing for your infant.

Skip to section 13.1, I think it is. It says on EVERY vaccine insert, “This product has not been tested for carcinogenicity, cell mutations nor fertility issues”. Then they claim that “haven’t seen any correlation with fertility problems, childhood cancers nor gene mutations with vaccines.” No, they haven’t seen it BECAUSE they haven’t LOOKED nor tested for it, as they SAY in Section 13!

Also note that the subject of some of this excellent write up by Dr. Malone, diabetes, is on most of the vaccine inserts as a possible adverse event from MOST of the childhood shots. Please note that other possible adverse events that also screw up metabolism and the gut biome are mentioned as well.

Please rethink your policy on vaccines, people, because all the berberine and natural

stuff in the world can’t fix what Big pHARM-us being to break, Day 1!

James Schwartz's avatar

22 years at the FDA. Leave with a nice pension then head to J&J to a cushy 250k/yr job because of your connections at the FDA which of course could be useful at a later date. There should be a law that if you work in the HHS behemoth you are barred for a decade before working in the private big Pharma sector. The corruption is immediate and public.

Andrew_D's avatar

You must know why they insisted that Remdesivir be included in the trial you mentioned. That would have ensured the trial’s failure. It didn’t get the nickname “Run, Death Is Near” because it was safe.

Tory77simplifyfocus's avatar

It was a tragic time in our history.

Ross Bausone's avatar

Wife and I both took a combination of Ivermectin, Vitamin K and a couple other recommended things when we contracted Covid (per the test we received in the mail). Symptoms subsided within 24 hours of taking the combination. We had both had the Vax before (obviously of no value to us).

We would use it again in a hot minute if we ever had Covid again!

Jean's avatar

Very informative. Thank you for sharing.

I've been interested in berberines possibilities. Then gathered it was a likely no go. I suspect that relates to my warfarin. My attending MD is a pretty hide bound AMA true follower. Time for your vaxs sort.

So glad for yourselves and the IMA spreading its wings.

Off topic: So interesting that more is coming out about the Fabrizio poll. Night and day as relates to the initial report. I wonder if it will get shared where it needs to be. In the meantime, our leader is evidently off to end another war. So for better or worse, we'll see...

Sent this essay to my boss lady. She and hers might well benefit and that would be a very good thing.

A.J. Foster's avatar

Back to basic facts of all. The FDA is influenced by the drug makers and will stop anything that interupte the monet flow.

Celia M Paddock's avatar

Thank you for not dissing GLP-1s. I'm one of those people whose lives have been altered. As happens all too often with people with type 1 diabetes, lower A1c levels often come with weight gain. Then there's the problem that, as we age, we may get type 2 diabetes as well (they are very different conditions, despite both being related to insulin). My endocrinologist prescribed a GLP-1 when my weight--which had been higher than it should have been for years, with no success from dieting--started rising as my A1c dropped (improved pump control). Not only has my weight dropped (slowly but steadily), it has had a noticeable impact on my blood glucose (a sure sign that I do have type 2 layered over my type 1).

Thomas A Braun RPh's avatar

Do you know your blood value of D?

LoverOfHills's avatar

It's so easy, Thomas. Everyone should know their D3 level. WalkInLab.com.

Celia M Paddock's avatar

I haven’t had it tested recently, but the last time I did, I was on the low end of ‘normal’ despite taking 4,000IU daily. Since then, I’ve taken 6,000IU in winter and 5,000IU in summer. Recently read about macrodoses, and I’ve gone up to 10,000IU. Jury is still out on that.

LoverOfHills's avatar

WalkInLab.com - easy to get blood tests, cause no doc prescription needed, they coordinate with LabCorp and Quest. 45$/D3 blood test, so, easy schmeezy to get it checked, as you tweak D supplements. I found I only needed to add to my daily One a Day, 2000 IUs of D to get(and stay) my level to high 60'sng.

Thomas A Braun RPh's avatar

You must live where it is sunny year round! Thanks for the reminder about WalkinLab!

I don’t know if that is allowed in all states .

I have to take 5000 IU’s daily to hit 70!